In this paper, the application of the second law of thermodynamics to boundary layer flow over a stretching surface with the presence of slip boundary condition and nanoparticles fractions is investigated. The model applied for the nanofluid incorporates the effects of Brownian motion as well as thermophoresis. A similarity solution is proposed. The solution depends on the Lewis number Le, Prandtl number Pr, slip factor b, suction/injection parameter λ, Brownian motion number Nt and thermophoresis number Nt. The effects of these six parameters on velocity, concentration and temperature profiles are discussed. The influence of the same parameters, the Reynolds number and the dimensionless group parameter on the entropy generation is also studied. It was found that the entropy generation was strongly impacted by these parameters.

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