The objective was to know the perceptions and strategies of nursing professionals about the medication dispensing process carried out in a central nursing station of an emergency care unit. This is an exploratory, descriptive, qualitative research carried out with 43 nursing professionals. Data were collected from June to August 2018 through semi-structured interviews with subsequent discursive textual analysis. Two units were formed regarding weaknesses/difficulties and strategies for the medication dispensing process at the central nursing station. These units resulted in seven categories: prescription, dilution/time; training and elaboration of a standard manual; professional attention; extinction of the central nursing station; and idealization of a central station in the unit. The weaknesses were: insecurity in administering medications diluted by colleagues, prescription errors, and inattention to the stages of the process. Professional updates, training, elaboration of manuals, and a greater number of professionals were suggested as strategies.